Publications

Year: 2026 | 2025 | 2024 | 2023 | 2022 | 2021 | 2020 and earlier

2026

Chae HD, Shrestha U, Das M, Vasanawala MS, Behl D, Davar D, Srinivas S, Colevas AD, Sunwoo JB, Del Mar N, Pierini M, Guillen M, Garcia J, Omidvari N, Gupta N, Cabrera H, Blecha J, Cherry SR, VanBrocklin H, Flavell RR, Moslehi J, Seo Y, Levi J. (2026) Mitochondrial Imaging Detects Early Cardiac Changes Following Cancer Immunotherapy. Clin Cancer Res. 10.1158/1078-0432.CCR-26-0277. doi: 10.1158/1078-0432.CCR-26-0277.

2025

Mehadji B, Abdelhafez YG, Alavi A, Chung KJ, Karakatsanis NA, Omidvari N, Nardo L. (2025) Long Axial Field of View PET: A New Era of Quantitative PET Imaging for Prospective Applications Beyond Classical Theranostics. PET Clin; S1556-8598(25)00066-5. doi: 10.1016/j.cpet.2025.07.009.
Omidvari N, Shanina E, Leung EK, Sun X, Li Y, Mulnix T, Gravel P, Henry S, Matuskey D, Volpi T, Jones T, Badawi RD, Li H, Carson RE, Qi J, Cherry SR. (2025) Quantitative Accuracy Assessment of the NeuroEXPLORER for Diverse Imaging Applications: Moving Beyond Standard Evaluations. J Nucl Med; 66(1):150-157. doi: 10.2967/jnumed.124.268309.
Zhu Y, Li S, Xie Z, Leung EK, Bayerlein R, Omidvari N, Cherry SR, Qi J, Badawi RD, Spencer BA, Wang G. (2025) Feasibility of PET-enabled dual-energy CT imaging: First physical phantom and initial patient study results. Eur J Nucl Med Mol Imaging; 52(5):1912-1923. doi: 10.1007/s00259-024-06975-5.

2024

Omidvari N, Levi J, Abdelhafez YG, Wang Y, Nardo L, Daly ME, Wang G, Cherry SR (2024) Total-body Dynamic Imaging and Kinetic Modeling of [18F]F-AraG in Healthy Individuals and a Non-Small Cell Lung Cancer Patient Undergoing Anti-PD-1 Immunotherapy. J Nucl Med; 65(9):1481-1488. doi: 10.2967/jnumed.123.267003.

Total-Body Dynamic Imaging and Kinetic Modeling of [18F]F-AraG in Healthy Individuals and a Non–Small Cell Lung Cancer Patient Undergoing Anti–PD-1 Immunotherapy

The study was the first use of dynamic imaging and kinetic modeling with the [¹⁸F]F-AraG tracer and highlights the promise of [¹⁸F]F-AraG dynamic imaging as a noninvasive biomarker for quantifying the immune response to immunotherapy in cancer patients.

Li H, Badawi RD, Cherry SR, Fontaine K, He L, Henry S, Hillmer AT, Hu L, Khattar N, Leung EK, Li T, Li Y, Liu C, Liu P, Lu Z, Majewski S, Matuskey D, Morris ED, Mulnix T, Omidvari N, Samanta S, Selfridge A, Sun X, Toyonaga T, Volpi T, Zeng T, Jones T, Qi J, Carson RE. (2024) Performance Characteristics of the NeuroEXPLORER, a Next-Generation Human Brain PET/CT Imager. J Nucl Med; 65(8):1320-1326. doi: 10.2967/jnumed.124.267767.
Mingels C, Spencer BA, Nalbant H, Omidvari N, Rokni M, Rominger A, Sen F, Cherry SR, Badawi RD, Abdelhafez YG, Nardo L. (2024) Dose Reduction in Pediatric Oncology Patients with Delayed Total-Body [18F]FDG PET/CT. J Nucl Med; 65(7):1101-1106. doi: 10.2967/jnumed.124.267521.
Bayerlein R, Spencer BA, Leung EK, Omidvari N, Abdelhafez YG, Wang Q, Nardo L, Cherry SR, Badawi RD. (2024) Development of a Monte Carlo-based scatter correction method for total-body PET using the uEXPLORER PET/CT scanner. Phys Med Biol; 69(4). doi: 10.1088/1361-6560/ad2230.

2023

Omidvari N, Jones T, Price PM, Ferre AL, Lu J, Abdelhafez YG, Sen F, Cohen SH, Schmiedehausen K, Badawi RD, Shacklett BL, Wilson I, Cherry SR. (2023) First-in-human immunoPET imaging of COVID-19 convalescent patients using dynamic total-body PET and a CD8-targeted minibody. Sci Adv; 9(41):eadh7968. doi: 10.1126/sciadv.adh7968.
First-in-human immunoPET imaging of COVID-19 convalescent patients using dynamic total-body PET and a CD8-targeted minibody

This study presents the first use of dynamic positron emission tomography (PET) and kinetic modeling for in vivo measurement of CD8⁺ T cell biodistribution in humans. A ⁸⁹Zr-labeled CD8-targeted minibody (⁸⁹Zr-Df-Crefmirlimab) was used with total-body PET in healthy individuals (N = 3) and coronavirus disease 2019 (COVID-19) convalescent patients (N = 5). Kinetic modeling results aligned with T cell–trafficking effects expected in lymphoid organs. Total-body dynamic imaging revealed increased CD8 density in bone marrow of COVID-19 convalescent patients compared to controls, with an increasing trend between 2 and 6 months after infection.
Wang Y, Nardo L, Spencer BA, Abdelhafez YG, Li EJ, Omidvari N, Chaudhari AJ, Badawi RD, Jones T, Cherry SR, Wang G. (2023) Total-Body Multiparametric PET Quantification of 18F-FDG Delivery and Metabolism in the Study of Coronavirus Disease 2019 Recovery. J Nucl Med; 64(11):1821-1830. doi: 10.2967/jnumed.123.265723.
Bayerlein R, Spencer BA, Abdelhafez YG, Cherry SR, Badawi RD, Omidvari N. (2023) Numerical investigation reveals challenges in measuring the contrast recovery coefficients in PET. Phys Med Biol; 68(21). doi: 10.1088/1361-6560/ad00fa.

2022

Abdelhafez Y, Raychaudhuri SP, Mazza D, Sarkar S, Hunt HL, McBride K, Nguyen M, Caudle DT, Spencer BA, Omidvari N, Bang H, Cherry SR, Nardo L, Badawi RD, Chaudhari AJ. (2022) Total-Body 18F-FDG PET/CT in Autoimmune Inflammatory Arthritis at Ultra-Low Dose: Initial Observations. J Nucl Med; 63(10):1579-1585. doi: 10.2967/jnumed.121.263774.
Omidvari N, Cheng L, Leung EK, Abdelhafez YG, Badawi RD, Ma T, Qi J, Cherry SR. (2022) Lutetium background radiation in total-body PET-A simulation study on opportunities and challenges in PET attenuation correction. Front Nucl Med, Rising Stars in PET and SPECT Special Issue; 2:963067. doi: 10.3389/fnume.2022.963067.
Costa G, Spencer B, Omidvari N, Foster C, Rusnak M, Hunt H, Caudle DT, Pillai RT, Vu CT, Roncali E. (2022) Radioembolization Dosimetry with Total-Body 90Y PET. J Nucl Med; 63(7):1101-1107. doi: 10.2967/jnumed.121.263145.
Leung EK, Abdelhafez YG, Berg E, Xie Z, Zhang X, Bayerlein R, Spencer B, Li E, Omidvari N, Selfridge A, Cherry SR, Qi J, Badawi RD. (2022) Relating 18F-FDG image signal-to-noise ratio to time-of-flight noise-equivalent count rate in total-body PET using the uEXPLORER scanner. Phys Med Biol; 67(12):10.1088/1361-6560/ac72f1. doi: 10.1088/1361-6560/ac72f1.
Ng QK, Triumbari EKA, Omidvari N, Cherry SR, Badawi RD, Nardo L. (2022) Total-body PET/CT - First Clinical Experiences and Future Perspectives. Semin Nucl Med; 52(3):330-339. doi: 10.1053/j.semnuclmed.2022.01.002.
Varasteh Z, Braeuer M, Mohanta S, Steinsiek AL, Habenicht A, Omidvari N, Topping GJ, Rischpler C, Weber WA, Sager HB, Raes G, Hernot S, Schwaiger M. (2022) In vivo Visualization of M2 Macrophages in the Myocardium After Myocardial Infarction (MI) Using 68 Ga-NOTA-Anti-MMR Nb: Targeting Mannose Receptor (MR, CD206) on M2 Macrophages. Front Cardiovasc Med; 9:889963. doi: 10.3389/fcvm.2022.889963.

2021

Leung EK, Berg E, Omidvari N, Spencer BA, Li E, Abdelhafez YG, Schmall JP, Liu W, He L, Tang S, Liu Y, Dong Y, Jones T, Cherry SR, Badawi RD. (2021) Quantitative accuracy in total-body imaging using the uEXPLORER PET/CT scanner. Phys Med Biol; 66(20):10.1088/1361-6560/ac287c. doi: 10.1088/1361-6560/ac287c.
Spencer BA, Berg E, Schmall JP, Omidvari N, Leung EK, Abdelhafez YG, Tang S, Deng Z, Dong Y, Lv Y, Bao J, Liu W, Li H, Jones T, Badawi RD, Cherry SR. (2021) Performance Evaluation of the uEXPLORER Total-Body PET/CT Scanner Based on NEMA NU 2-2018 with Additional Tests to Characterize PET Scanners with a Long Axial Field of View. J Nucl Med; 62(6):861-870. doi: 10.2967/jnumed.120.250597.

2013 – 2020

Zatcepin A, Pizzichemi M, Polesel A, Paganoni M, Auffray E, Ziegler SI, Omidvari N. (2020) Improving depth-of-interaction resolution in pixellated PET detectors using neural networks. Phys Med Biol; 65(17):175017. doi: 10.1088/1361-6560/ab9efc.
Varasteh Z, Mohanta S, Robu S, Braeuer M, Li Y, Omidvari N, Topping G, Sun T, Nekolla SG, Richter A, Weber C, Habenicht A, Haberkorn UA, Weber WA. (2019) Molecular Imaging of Fibroblast Activity After Myocardial Infarction Using a 68Ga-Labeled Fibroblast Activation Protein Inhibitor, FAPI-04. J Nucl Med; 60(12):1743-1749. doi: 10.2967/jnumed.119.226993.
Omidvari N, Topping G, Cabello J, Paul S, Schwaiger M, Ziegler SI. (2018) MR-compatibility assessment of MADPET4: a study of interferences between an SiPM-based PET insert and a 7 T MRI system. Phys Med Biol; 63(9):095002. doi: 10.1088/1361-6560/aab9d1.
Omidvari N, Cabello J, Topping G, Schneider FR, Paul S, Schwaiger M, Ziegler SI. (2017) PET performance evaluation of MADPET4: a small animal PET insert for a 7 T MRI scanner. Phys Med Biol; 62(22):8671-8692. doi: 10.1088/1361-6560/aa910d.
Omidvari N, Sharma R, Ganka TR, Schneider FR, Paul S, Ziegler SI. (2017) Characterization of 1.2×1.2 mm2 Silicon Photomultipliers with Ce:LYSO, Ce:GAGG, and Pr:LuAG Scintillation Crystals as Detector Modules for Positron Emission Tomography. J Instrum; 12(4): P04012. doi: 10.1088/1748-0221/12/04/P04012.
Omidvari N and Schulz V. (2015) Characterization of Sensitivity Encoded Silicon Photomultiplier (SeSP) with 1-Dimensional and 2-Dimensional Encoding for High Resolution PET/MR. IEEE Trans Nucl Sci; 62(3): 679-687. doi: 10.1109/TNS.2015.2422374.
Schulz V, Berker Y, Berneking A, Omidvari N, Kiessling F, Gola A, Piemonte C. (2013) Sensitivity encoded silicon photomultiplier--a new sensor for high-resolution PET-MRI. Phys Med Biol; 58(14):4733-48. doi: 10.1088/0031-9155/58/14/4733.